Viktoria Plzeň are yet to lose a match in UEFA Europa League play and will look to avoid their first stumble as they defy Panathinaikos in Greece.

Ludogorets hope to carry their momentum after securing a playoff spot in the last contest of the previous stage in the first meeting with Ferencváros.

Crvena Zvezda head to France for the first bout of the playoff tie versus Lille, with the French club having won thrice and lost once at home so far.

Two of the main contenders to win the UEFA Europa League meet in Scotland in the first leg of their contest, with a Round of 16 berth on the line.

PAOK host Celta at Toumba Stadium in the opening leg of their UEFA Europa League meeting as they begin fighting for a spot in the Round of 16.

Fenerbahçe and Nottingham Forest meet in Turkey in a highly anticipated UEFA Europa League clash for the first leg of their playoff matchup.

Genk just missed out on an automatic Round of 16 spot and hope to continue their strong continental campaign while visiting Dinamo Zagreb in Croatia.

Brann just made the playoff-round cut despite five straight winless games in the competition and need their best as they host a skilled Bologna squad.

Young Boys need a win to secure safety to the playoffs against Stuttgart, which can still make the top eight if they prevail and get some help.

Brann must avoid a disappointing ending in order not to drop out of a knockout stage spot against Strum Graz, which, instead, are already out.

Real Betis hold the eighth position only by goal differential as they visit a Feyenoord squad aiming for a victory to have a chance to advance.

Porto need a win to have a chance of automatic qualification to the Round of 16. Instead, Rangers have already been ousted heading into the last tilt.