Genk hope to avoid a second straight loss and a potential slide out of qualification when visiting Utrecht, which are yet to win in the competition.

Stuttgart and Roma reside right below the qualification to the Round of 16, with three points likely to give the winner one of the eight spots.

RB Salzburg and Basel meet, fighting for a spot in the knockout round, with Basel possibly in with a win, while RB Salzburg will need some luck too.

Rangers are six points from the knockout stage and are on the verge of being eliminated, while Ludogorets are on the prowl for a win for safety.

Nice will be fighting for pride as they have already bowed out, while Go Ahead Eagles will make a push for qualification, currently two points off.

Ferencváros look to remain undefeated in UEFA Europa League play as they host Panathinaikos, which are in search of a good result to advance.

Dinamo Zagreb and FCSB are one and two points, respectively, from qualification, both needing a win to keep their UEFA Europa League campaigns alive.

Lille and Celta collide both sitting at nine points, with either likely to advance with a win but potentially on the brink of elimination with a loss.

Braga will more than likely secure a Round of 16 spot if they can earn a home win against Nottingham Forest, which are bidding for the same goal.

Lyon sit atop the UEFA Europa League table and travel to Switzerland to face Young Boys, which need a win to secure their spot in the knockout round.

Viktoria Plzeň appear to be set for a knockout phase spot with two matches to go. Porto sit on the brink of falling from a Round of 16 placement.

Real Betis travel to Greece still undefeated in the competition. PAOK sit just four points from the safety of a knockout phase qualification spot.