SK Rapid is in search of its first UEFA Europa Conference League win this season as they host an Omonoia squad that earned its first win last game.

Crystal Palace hopes to avoid another loss against a Shelbourne squad without a win and three straight losses in the Conference League.

Celje looks to avenge their first loss in the competition from the last game against on the road against Rijeka.

Raków will look to protect their home field as they face Zrinjski, with both teams in good form after wins last time out.

Mainz is trying to avenge their first loss in UEFA Conference League play last time out as they face a mid-table Lech Poznań in Poland.

Sigma Olomouc travels to face L. Red Imps in hopes of turning two straight UEFA Europa Conference League wins into a third.

KuPS Kuopio and Lausanne-Sport meet in Kuopio, Finland, after both squads suffered a loss in their last UEFA Conference League game.

Hamrun Spartans earned their first win in UEFA Conference League play last match and will hope to carry that form against Shakhtar Donetsk.

Strasbourg continues in the Conference League without a loss and looks to carry on against Scottish side Aberdeen.

U. Craiova looks to keep building momentum and earn a third straight win as they host a Sparta Praha team only ahead in the table on goal differential.

Two teams outside the qualification zone meet for a UEFA Conference League match as Slovan Bratislava and Shkëndija face off at Ecolog Arena.

AEK Athens and Samsunspor meet in Samsun, Turkey, for a top-ten battle in UEFA Conference League play.