Panathinaikos kick off their run in the Europa League in Switzerland against Young Boys, with both sides eyeing a spot in the top 24 of the league.

Lyon had a rocky road to the Europa League, but will hope to make the most of their chance when they kick off against Utrecht in the opening match.

Celta travel to Germany to take on a Stuttgart side who lost their starting striker and are looking to bounce back in the Europa League.

Porto take on RB Salzburg in the UEFA Europa League, with both clubs hoping to make a deep run after prior seasons in the Champions League.

Rangers were embarrassed in the Champions League final qualifying round, and will hope to bounce back against Genk in the Europa League opener.

Viktoria Plzen face off against Ferencvaros in the UEFA Europa League, with three points a must if either club wants to qualify from the league stage.

Aston Villa are off to a slow start in the Premier League, but have the chance to turn it around in Europe with an opening match against Bologna.

Brann open a surprise European run against Lille in what could be one of the toughest matches of the league phase against the French giants.

FCSB and Go Ahead Eagles are both hoping to make a surprise run through the league phase, making three points in the opener crucial for either club.

Nottingham Forest are back in European competition under new boss Ange Postecoglou, and will hope for a quick start in Spain against Real Betis.

Roma take on Nice with both clubs hoping to kick start deep runs in the UEFA Europa League, with eyes on a top eight finish.

Malmo FF are coming off a horrible end to the domestic season, but will hope to turn it around against Ludogorets in the UEFA Europa League.